As to usage, the directions say one or two "pumps" once or twice a day. I'm using one pump at bedtime and it works well to alleviate morning stiffness and swelling.
A week later my foot neuropathy was especially bad as was my sciatica. I rubbed the cream into my feet up to above my ankles, then applied some cream my tailbone all the way down both sides of my legs where the sciatica hurts the most.
My results were freaking awesome! In addition to the practically instant relief of my neuropathy pain, within half an hour I noticed that the arthritis in my back and my hands was barely noticeable for the first time in YEARS! All, and I do mean ALL, of my pains were either gone or so reduced that they were below the conscious level. I was able to WALK!
AND an added bonus was a day without extreme anxiety.
I ran out unexpectedly, though. The bottle really should have a way to determine how much remains.
I love this stuff but it’s SO expensive. Even with the subscription option.